Sinus in general refers to a cavity or channel and specifically refers to an air cavity in bone, as in the bones of the face and skull. Sinusitis is the inflammation of a sinus, usually on the parts of the face that link with the nose and may therefore be caused by the spread of infection from the nose. Headaches and tenderness over the affected sinus are typical symptoms, with a pus-containing discharge from the nose. Persistent infection may necessitate surgery to drain the sinus.

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